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The states where the most tobacco gets grownNorth Carolina and Kentuckyboth rank among the top 10 states for lowest taxes on cigarettes, and also among the top 10 for highest number of smoking-related cancer deaths
The pleiotropic effects of tobacco smoke on the immunostimulatory function of DCs are further illustrated by a study reporting a diminished capacity of DCs from cigarette smoke-exposed mice to induce IL-2 production by T cells, which was associated with a decreased antigen-specific T-cell proliferation in vivo
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The trend for Kentucky has remained flat, while California has improved during that time
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